Polysaccharide aerogels are promising delivery systems for a wide range of drugs due to their high surface area and mesoporous structure. Several formulations for oral, pulmonary, or topical drug delivery were successfully tried for the development of medicines with a positive impact on healthcare services.
Previous studies about polysaccharides for colonic drug delivery demonstrate that these materials present pH resistance and enzymatic resistance properties. In this review article, different possibilities to develop polysaccharide aerogels for colonic drug delivery formulations orally administered are presented. The characteristics of the gastrointestinal tract, as well as the aerogel composition, production techniques, and release kinetics of polysaccharide aerogels previously studied in the literature, were critically discussed for the intended colonic use.
The work entitled “Aerogels as Carriers for Oral Administration of Drugs: An Approach towards Colonic Delivery” has been published in Pharmaceutics journal (Q1; IF: 5.4) in November 2023. This work was developed within the framework of BioAerogel2Heal project.
Recent Comments